This product is a DS-1 B cell engineering tool based on the Solid lipid nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (AAVS1-SpCas9-NLS-Cas9-RS-1) genome editor.
| Host Cell | DS-1 |
| Target | NEUROG2 |
| Insert Clone | 3B2CR |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | AntimiR-21, doxorubicin (DOX) |
| Particle Size | 20-2850 |
| Charge (mv) | 10 to 30 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | RABV |
| Vector Name | BCpCDH8 |
| Targeting Diseases | Breast cancer; Lung cancer; Colorectal cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.