This product is a Toledo B cell engineering tool based on the Solid lipid nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-289-tracr RNA-Cas9-L755507) genome editor.
| Host Cell | Toledo |
| Target | NEUROG2 |
| Insert Clone | D2CR3DCR |
| Safe Harbor Sites (SHS) | SHS-289 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | L755507 |
| Targeting Strategy | pH responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Paclitaxel, chlorin e6 |
| Particle Size | 10-1000 |
| Charge (mv) | 10 to 45 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Lung cancer; Colorectal cancer |
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