This product is a Ramos (RA 1) B cell engineering tool based on the Gold nanoparticles (LRP-1 targetingpeptide/Lipoproteinreceptor-related protein-1) delivery system and CRISPR-based (SHS-321-crispr RNA-SpCas9-SCR7 pyrazine) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | NEUROG3 |
| Insert Clone | 3G7CR |
| Safe Harbor Sites (SHS) | SHS-321 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Mouse genome E-2 |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | LRP-1 targeting peptide/Lipoprotein receptor-related protein-1 |
| Active Agents | DOX |
| Particle Size | <1000 |
| Charge (mv) | -25 to -47 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Lung cancer; Breast cancer; Prostate cancer; Melanoma |
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