Dimethyl Pimelimidate Dihydrochloride Homobifunctional Crosslinker (CAT#: OLY-1023-YS121)

Description

DMP is a homobifunctional, amine-reactive crosslinker. It possesses two reactive imidoester groups, separated by a 7-carbon (C7) aliphatic spacer. Imidoesters react specifically with primary amines (lysines) at basic pH (8.0-10.0) to form stable amidine bonds. A key advantage of this reaction is that the amidine linkage retains the original positive charge of the amine, which can be critical for preserving the native structure and function of a protein. DMP is used for intramolecular (within one protein) or intermolecular (between proteins) crosslinking studies.

Molecular Weight

259.17

Purity

>98.0%

Formula

C₉H₁₈N₂O₂·₂HCl

Product Type

Homobifunctional Crosslinkers

Group 1

Other

Group 2

Other

Form (20 deg.C)

Solid

Storage Condition

Store under inert gas, 2-8°C

Molecular Structure