Cas No.: 204521-63-1
PRODUCT INFORMATION
Description
This reagent is designed to covalently attach a palmitic acid (C16) albumin-binding motif to a molecule. It uses a glutamic acid scaffold. The N-terminus is acylated with palmitic acid. The gamma-carboxyl is protected as an acid-labile t-butyl (OtBu) ester. The alpha-carboxyl is activated as an amine-reactive N-hydroxysuccinimide (OSu) ester. This allows for the direct, one-step conjugation of the C16-lipid tail (which binds non-covalently to albumin) onto a primary amine of a drug or peptide, extending its in vivo half-life.
Molecular Weight
538.73
Purity
>96.0%
Formula
C₂₉H₅₀N₂O₇
Product Type
Albumin Binding Conjugation Reagents
Group 1
NHS
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, -20°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- Mal-PEG2-CH2CH2Mal PEGylation Crosslinker (CAT#: OLY-1023-YS125)
- 6-Maleimidohexanoic Acid Heterobifunctional Crosslinker (CAT#: OLY-1023-YS11)
- 3-Maleimido-propionic NHS (BMPS) Heterobifunctional Crosslinker (CAT#: OLY-1023-YS108)
- Fmoc-N-amido-PEG6-acid PEGylation Crosslinker (CAT#: OLY-1023-YS6)
- m-PEG4-amine PEGylation Crosslinker (CAT#: OLY-1023-YS234)
- 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium Chloride (CAT#: OLY-1023-YS292)
- 4,4-Diphenylcyclohexanol (CAT#: OLY-1023-YS180)
- [4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenyl]methanamine Hydrochloride Heterobifunctional Crosslinker (CAT#: OLY-1023-YS82)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.