Cas No.: 28537-70-4
PRODUCT INFORMATION
Description
This is a homobifunctional, sulfhydryl-reactive crosslinker. It consists of two maleimide groups separated by a short, 4-carbon (C4) aliphatic spacer. Maleimide groups react specifically with thiols (cysteines) at neutral pH (6.5-7.5) to form stable, non-cleavable thioether bonds. BMB is primarily used to crosslink two different thiol-containing molecules (e.g., two peptides) or to induce intramolecular crosslinks between two cysteine residues within the same protein. This can be used to study or stabilize protein tertiary/quaternary structure.
Molecular Weight
248.24
Purity
>98.0%
Formula
C₁₂H₁₂N₂O₄
Product Type
Homobifunctional Crosslinkers
Group 1
Maleimide
Group 2
Maleimide
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, <0°C
Molecular Structure
For Research Use Only | Not For Clinical Use
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