Cas No.: 55750-53-3
PRODUCT INFORMATION
Description
This non-cleavable, heterobifunctional crosslinker is a longer-chain analogue of 4-Maleimidobutyric Acid. It contains a sulfhydryl-reactive maleimide group and a terminal carboxylic acid, separated by a flexible 6-carbon (C6) aliphatic spacer. The extended C6 spacer provides greater reach and can help overcome steric hindrance. The maleimide group targets thiols (cysteines, pH 6.5-7.5), while the carboxylic acid can be activated (EDC/NHS) to couple with primary amines (lysines). It is a staple reagent for conjugating peptides, proteins, or haptens.
Molecular Weight
211.22
Purity
>98.0%
Formula
C₁₀H₁₃NO₄
Product Type
Heterobifunctional Crosslinkers
Group 1
Maleimide
Group 2
COOH
Form (20 deg.C)
Solid
Storage Condition
2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use
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