N,N'-(Naphthalene-1,5-diyl)bis[2-(aminooxy)acetamide] Homobifunctional Crosslinker (CAT#: OLY-1023-YS161)

Description

This is a homobifunctional crosslinker featuring two aminooxy (oxyamine) groups, separated by a rigid, fluorescent naphthalene spacer. Aminooxy groups are highly specific for reacting with carbonyl groups (aldehydes and ketones) at a mildly acidic pH (4-5) to form stable oxime bonds. This highly specific "carbonyl chemistry" is bioorthogonal. This linker is used to crosslink two molecules containing aldehydes or ketones (e.g., periodate-oxidized glycans on antibodies). The rigid naphthalene core provides a defined spacing and can also serve as a fluorescent reporter.

Molecular Weight

304.31

Purity

>95.0%

Formula

C₁₄H₁₆N₄O₄

Product Type

Homobifunctional Crosslinkers

Group 1

Other

Group 2

Other

Form (20 deg.C)

Solid

Storage Condition

Store under inert gas, 2-8°C

Molecular Structure