Biotin Hydrazide Biotins Conjugation Reagent (CAT#: OLY-1023-YS184)

Description

Biotin Hydrazide is a biotinylation reagent featuring a terminal hydrazide group (-NH-NH2). The hydrazide group reacts specifically with carbonyl groups (aldehydes and ketones) at a mildly acidic pH (4-5) to form a stable hydrazone bond. This makes it the ideal reagent for labeling biomolecules containing aldehyde handles. Its most common application is the biotinylation of glycoproteins (e.g., antibodies) after their carbohydrate (sialic acid) portions have been selectively oxidized with sodium periodate to generate aldehyde groups.

Molecular Weight

258.34

Purity

>98.0%

Formula

C₁₀H₁₈N₄O₂S

Product Type

Biotins and Streptavidins

Group 1

Biotin

Group 2

Other

Form (20 deg.C)

Solid

Storage Condition

2-8°C

Molecular Structure