Fmoc-N-amido-PEG6-acid PEGylation Crosslinker (CAT#: OLY-1023-YS6)

Description

This is a heterobifunctional, hydrophilic PEGylation linker. It features a terminal carboxylic acid and a base-labile Fmoc-protected amine, connected by a 6-unit polyethylene glycol (PEG) chain. The carboxylic acid can be activated (e.g., with EDC/NHS) to couple with primary amines. The Fmoc group provides orthogonal protection, removable under mild basic conditions (e.g., piperidine) to expose the amine for a subsequent step. It is widely used in solid-phase peptide synthesis (SPPS) or to introduce a hydrophilic PEG spacer with a protected amine handle onto a biomolecule.

Molecular Weight

575.66

Purity

>98.0%

Formula

C₃₀H₄₁NO₁₀

Product Type

Heterobifunctional Crosslinkers ; PEGylation Reagents

Group 1

COOH

Group 2

Other

Form (20 deg.C)

Liquid

Storage Condition

Store under inert gas, -20°C

Molecular Structure