m-PEG8-NHS Ester PEGylation Crosslinker (CAT#: OLY-1023-YS252)

Description

This is a monofunctional, amine-reactive PEGylation reagent with a medium-length spacer. It features an 8-unit polyethylene glycol (PEG) chain, capped with an inert methoxy (m) group and functionalized with an N-hydroxysuccinimide (NHS) ester. The NHS ester reacts with primary amines (lysines). This reagent is commonly used for "PEGylating" proteins and peptides to attach a hydrophilic, inert polymer chain. This can improve solubility, increase in vivo half-life, and reduce immunogenicity or non-specific binding in diagnostic assays.

Molecular Weight

509.55

Formula

C₂₂H₃₉NO₁₂

Product Type

PEGylation Reagents

Group 1

NHS

Form (20 deg.C)

Liquid

Storage Condition

Store under inert gas, <0°C

Molecular Structure