Mal-PEG3-CH2CH2Mal PEGylation Crosslinker (CAT#: OLY-1023-YS126)

Description

This is a homobifunctional, sulfhydryl-reactive PEGylation crosslinker, a longer analogue of the PEG2 version. It features two maleimide groups separated by a hydrophilic 3-unit polyethylene glycol (PEG) spacer. The maleimide groups react specifically with thiols (cysteines) at pH 6.5-7.5 to form stable thioether bonds. The longer, flexible PEG3 spacer provides greater reach for crosslinking two cysteines that are further apart, either within a protein or between two different molecules. The PEG spacer enhances water solubility.

Molecular Weight

352.34

Purity

>98.0%

Formula

C₁₆H₂₀N₂O₇

Product Type

Homobifunctional Crosslinkers ; PEGylation Reagents

Group 1

Maleimide

Group 2

Maleimide

Form (20 deg.C)

Solid

Storage Condition

Store under inert gas, -20°C

Molecular Structure