Cas No.: 86099-06-1
PRODUCT INFORMATION
Description
This is a homobifunctional, sulfhydryl-reactive PEGylation crosslinker, a longer analogue of the PEG2 version. It features two maleimide groups separated by a hydrophilic 3-unit polyethylene glycol (PEG) spacer. The maleimide groups react specifically with thiols (cysteines) at pH 6.5-7.5 to form stable thioether bonds. The longer, flexible PEG3 spacer provides greater reach for crosslinking two cysteines that are further apart, either within a protein or between two different molecules. The PEG spacer enhances water solubility.
Molecular Weight
352.34
Purity
>98.0%
Formula
C₁₆H₂₀N₂O₇
Product Type
Homobifunctional Crosslinkers ; PEGylation Reagents
Group 1
Maleimide
Group 2
Maleimide
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, -20°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- Azido-PEG4-amine PEGylation Crosslinker (CAT#: OLY-1023-YS65)
- Amino-PEG3-acid tert-butyl Ester Heterobifunctional Crosslinker (CAT#: OLY-1023-YS97)
- Azido-PEG4-acid (CAT#: OLY-1023-YS67)
- Dithiobis(succinimidyl propionate) (DSP) Homobifunctional Crosslinker (CAT#: OLY-1023-YS141)
- Bis-PEG5-NHS Ester PEGylation Crosslinker (CAT#: OLY-1023-YS167)
- Alloc-Val-Cit-PAB-OH Enzyme Cleavable Linker for ADC (CAT#: OLY-1023-YS271)
- 3-N-Maleimidobenzoic Acid-NHS (MBS) Heterobifunctional Crosslinker (CAT#: OLY-1023-YS106)
- Di(N-succinimidyl) Pimelate Homobifunctional Crosslinker (CAT#: OLY-1023-YS136)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.