Home > Products > CD22 & saporin > Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Diabody-Fc)

Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Diabody-Fc)  (BSDBF-053)

Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-CD22 and anti-saporin antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Lymphoma therapy.

Specifications

Targets
CD22 & saporin
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD22
Host Animal 1
Mouse
Target 2
saporin
Host Animal 2
Mouse
Application
FuncS; Pretargeting system for immunotoxin delivery
Related Disease
Lymphoma

Targets

Target 1
CD22
Gene ID
UniProt ID
Alternative Names
CD22; CD22 molecule; Cluster of differentiation 22; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2
Target 2
saporin
Alternative Names
Saporin; Ribosome inactivating protein; RIP

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