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Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (scFv-CH1/CL)  (CAT#: BSCC-140)

Recombinant Anti-CEA x Anti-HSG Bispecific Antibody (scFv-CH1/CL) is designed to be expressed as two chains. One scFv from an anti-CEA antibody variable domain is fused to CH1 and the other scFv from an anti-HSG antibody variable domain fused to CL, or vice versa. And the CH1 and CL domains are linked covalently via a natural disulfide bond. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer imaging and therapy.
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Specifications

Targets
CEA & HSG
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Pretargeting system for radioimaging and radiotherapy
Related Disease
Breast cancer; Ovary cancer; Colon cancer; Lung cancer

Targets

Target 1
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
HSG
Alternative Names
histaminyl-succinyl-glycine; HSG
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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