Home > Products > HSG & TROP2 > Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Bibody)

Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Bibody)  (BIBD-170)

Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (Bibody) is a Fab-scFv format that uses heterodimeric Fab as a scaffold, and a scFv region linked to one of its heavy (Fd) or light (L) chain. The scFv of the anti-HSG specificity is fused to the anti-HSG heavy or light chain of the Fab. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Pancreatic cancer; Breast cancer; Gastrointestinal cancer; Cancers imaging and therapy.

Specifications

Targets
HSG & TROP2
Type
Bibody
Species Reactivity
Human
Target 1
HSG
Host Animal 1
Mouse
Target 2
TROP2
Host Animal 2
Mouse
Application
FuncS; Pretargeting system for radioimaging and radiotherapy
Related Disease
Pancreatic cancer; Breast cancer; Gastrointestinal cancer; Cancers

Targets

Target 1
HSG
Alternative Names
histaminyl-succinyl-glycine; HSG
Target 2
TROP2
Gene ID
UniProt ID
Alternative Names
TACSTD2; tumor-associated calcium signal transducer 2; EGP1; GP50; M1S1; EGP-1; TROP2; Trop-2; GA7331; GA733-1; epithelial glycoprotein-1; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; pancreatic carcinoma marker protein GA7331; pancreatic carcinoma marker protein GA733-1; gastrointestinal tumor-associated antigen GA7331; membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; 40kD glycoprotein, identified by monoclonal antibody GA733

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