Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scFv-CH3) (BSFC-170)

Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scFv-CH3) contains two chains. The anti-HSG scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-TROP2 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Pancreatic cancer; Breast cancer; Gastrointestinal cancer; Cancers imaging and therapy.

Datasheet INQUIRY

Specifications

Targets

HSG & TROP2

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Pretargeting system for radioimaging and radiotherapy

Related Disease

Pancreatic cancer; Breast cancer; Gastrointestinal cancer; Cancers

Targets

Target 1

HSG

Alternative Names

histaminyl-succinyl-glycine; HSG

Target 2

TROP2

Gene ID

4070

UniProt ID

P09758

Alternative Names

TACSTD2; tumor-associated calcium signal transducer 2; EGP1; GP50; M1S1; EGP-1; TROP2; Trop-2; GA7331; GA733-1; epithelial glycoprotein-1; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; pancreatic carcinoma marker protein GA7331; pancreatic carcinoma marker protein GA733-1; gastrointestinal tumor-associated antigen GA7331; membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; 40kD glycoprotein, identified by monoclonal antibody GA733

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-HSG x Anti-TROP2 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-170)

Specifications

Targets

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