Name: Recombinant Human Anti-Nkp30 x Mouse Anti-HER2 Bispecific Antibody (scFv-Fc)
SKU: KN-0725-N68
Rating: 5 (1 reviews)

Recombinant Human Anti-Nkp30 x Mouse Anti-HER2 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-Nkp30 specificity or anti-HER2 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Breast cancer; Gastric cancer; Prostate cacncer; Ovarian cancer; Solid tumors therapy.

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Specifications

Targets

Nkp30 & HER2

Type

scFv-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Breast cancer; Gastric cancer; Prostate cacncer; Ovarian cancer; Solid tumors

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

Nkp30

Gene ID

259197

UniProt ID

O14931

Alternative Names

NCR3; Natural Cytotoxicity Triggering Receptor 3; CD337; Cluster of Differentiation 337; CLEC2D; C-Type Lectin Domain Family 2 Member D; LY94; Lymphocyte Antigen 94; 1C7; MALS; LY117; NKp30; Activating natural killer receptor p30; Natural killer cell p30-related protein

Target 2

HER2

Gene ID

2064

UniProt ID

P04626

Alternative Names

ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; human epidermal growth factor receptor 2; neuro/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-Nkp30 x Mouse Anti-HER2 Bispecific Antibody (scFv-Fc) (CAT#: KN-0725-N68)

Specifications

Targets

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