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CD248 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H252 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD3 Human CD248 Human Inquiry
T-BSDB-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD3 Mouse CD248 Mouse Inquiry
SCIGG-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (scIgG) Human Single chain IgGs CD3 Human CD248 Human Inquiry
FABVC-376 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Fab-sdAb-Fc) Human Fab-scFv/sdAb-Fc CD3 Mouse CD248 llama Inquiry
BSSG-376 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (sdAb-IgG) Human sdAb-IgG CD3 Mouse CD248 llama Inquiry
HCAB-021 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (sdAb-Fc-sdAb) Human sdAb-Fc-sdAb CD3 llama CD248 llama Inquiry
BIBD-376 Recombinant Anti-CD3 x Anti-CD248 VHH BispecificAntibody (Bibody) Human Bibody CD3 Mouse CD248 llama Inquiry
IGVHH-021 Recombinant Anti-CD3 x Anti-CD248 sdAb Bispecific Antibody (IgG-sdAb) Human IgG-sdAb CD3 Mouse CD248 llama Inquiry
BIVHH-021 Recombinant Anti-CD3 sdAb x Anti-CD248 sdAb Bispecific Antibody (Bi-sdAb) Human Bi-sdAb CD3 llama CD248 llama Inquiry
SCIGG-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (scIgG) Human Single chain IgGs CD3 Mouse CD248 Mouse Inquiry
FVTIG-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD3 Human CD248 Human Inquiry
FVTIG-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD3 Mouse CD248 Mouse Inquiry
BSSG-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD3 Human CD248 Human Inquiry
BSSG-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD3 Mouse CD248 Mouse Inquiry
IGLFV-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD3 Human CD248 Human Inquiry
IGLFV-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD3 Mouse CD248 Mouse Inquiry
BSGV-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD3 Mouse CD248 Mouse Inquiry
BSGV-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD3 Mouse CD248 Mouse Inquiry
BSDG-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD3 Human CD248 Human Inquiry
BSDG-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD3 Mouse CD248 Mouse Inquiry
BABFV-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD3 Human CD248 Human Inquiry
BABFV-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD3 Mouse CD248 Mouse Inquiry
FABVC-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD3 Human CD248 Human Inquiry
FABVC-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD3 Mouse CD248 Mouse Inquiry
SCDBC-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD3 Human CD248 Human Inquiry
SCDBC-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD3 Mouse CD248 Mouse Inquiry
BSDBC-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD3 Human CD248 Human Inquiry
BSDBC-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD3 Mouse CD248 Mouse Inquiry
SCDBF-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD3 Human CD248 Human Inquiry
SCDBF-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD3 Mouse CD248 Mouse Inquiry
BSFVF-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD3 Human CD248 Human Inquiry
BSFVF-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD3 Mouse CD248 Mouse Inquiry
BSDBF-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD3 Human CD248 Human Inquiry
BSDBF-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD3 Mouse CD248 Mouse Inquiry
BSTF-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD3 Mouse CD248 Mouse Inquiry
BSTF-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD3 Mouse CD248 Mouse Inquiry
BSCFV-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD3 Mouse CD248 Mouse Inquiry
BSCFV-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD3 Mouse CD248 Mouse Inquiry
MNAB-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Miniantibody) Human Miniantibody CD3 Mouse CD248 Mouse Inquiry
MNAB-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Miniantibody) Human Miniantibody CD3 Mouse CD248 Mouse Inquiry
BSFC-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD3 Mouse CD248 Mouse Inquiry
BSFC-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD3 Mouse CD248 Mouse Inquiry
BSCC-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD3 Mouse CD248 Mouse Inquiry
BSCC-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD3 Mouse CD248 Mouse Inquiry
BIBD-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Bibody) Human Bibody CD3 Mouse CD248 Mouse Inquiry
BIBD-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Bibody) Human Bibody CD3 Mouse CD248 Mouse Inquiry
FABFV-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Human CD248 Human Inquiry
FABFV-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD248 Mouse Inquiry
MiniB-H254 Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Minibody) Human Minibody CD3 Human CD248 Human Inquiry
MiniB-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Minibody) Human Minibody CD3 Mouse CD248 Mouse Inquiry
SCTB-H149 Recombinant Human Anti-CD248 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Human CD248 Human Inquiry
SCDB-H252 Recombinant Human Anti-CD3 x Anti-CD248 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Human CD248 Human Inquiry
FABIG-H252 Recombinant Human Anti-CD3 x Anti-CD248 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Human CD248 Human Inquiry
TRIB-H254 Recombinant Human Anti-CD3 x Anti-CD248 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Human CD248 Human Inquiry
BSIG-H252 Human Anti-CD3 x Anti-CD248 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Human CD248 Human Inquiry
CROSSAB-H252 Recombinant Human Anti-CD3 x Anti-CD248 Bispecific Antibody (CrossMab) Human CrossMab CD3 Human CD248 Human Inquiry
IGFV-H252 Recombinant Human Anti-CD3 x Anti-CD248 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Human CD248 Human Inquiry
BSDB-H252 Recombinant Human Anti-CD3 x Anti-CD248 Bispecific Antibody (Diabody) Human Diabody CD3 Human CD248 Human Inquiry
BSFAB-H252 Recombinant Human Anti-CD3 x Anti-CD248 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Human CD248 Human Inquiry
BSFV-H252 Recombinant Human Anti-CD3 x Anti-CD248 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Human CD248 Human Inquiry
SCTB-051 Recombinant Anti-CD248 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Mouse CD248 Mouse Inquiry
SCDB-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Mouse CD248 Mouse Inquiry
FABIG-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Mouse CD248 Mouse Inquiry
TRIB-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Mouse CD248 Mouse Inquiry
BSIG-078 Anti-CD3 x Anti-CD248 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Mouse CD248 Mouse Inquiry
CROSSAB-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (CrossMab) Human CrossMab CD3 Mouse CD248 Mouse Inquiry
IGFV-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Mouse CD248 Mouse Inquiry
BSDB-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Diabody) Human Diabody CD3 Mouse CD248 Mouse Inquiry
BSFAB-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD248 Mouse Inquiry
BSFV-078 Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD248 Mouse Inquiry

Background

CD248, a C-type lectin protein, is exhibited at high levels in pericytes of the tumor vascular system, malignant sarcoma cells as well as fibrotic interstitial cells. Under physiological conditions, CD248 is predominantly expressed during embryonic development and its presence in adult tissues is decidedly scarce. The ligands of CD248 incorporate collagen, fibronectin, and migration-stimulating factor.

Despite its structure being entirely characterized, the functions of CD248 remain incompletely elucidated. Research reveals that CD248 is involved in angiogenic signaling in the tumor milieu and exists as a component of the extracellular matrix (ECM), thus, it is extensively utilized as a molecular marker and interventional target in sarcomas or other diseases. Moreover, CD248 encompasses the Thrombospondin type 1 domain, implying its potential function in protein-protein interactions.

CD248 structure. (Teicher, 2019) Fig.1 CD248 structure.1

Reference

  1. Teicher. " CD248: A therapeutic target in cancer and fibrotic diseases." Cancers. 10 9 (2019): 993-1009.
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