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PSMA Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
KN-0825-JL8 Anti-PSMA x Anti-4-1BB Bispecific aptamer (RNA/RNA) Human Bispecific Aptamer PSMA 4-1BB Inquiry
KN-0825-N72 Recombinan Human Anti-PSMA x Human Anti-Vδ2 Bispecific Antibody (Tandem scFv) Human Tandem scFv PSMA Human Vδ2 Human Inquiry
T-BSDB-H276 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD3 Human PSMA Human Inquiry
T-BSDB-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Tandem Diabody) Human Tandem Diabody CD3 Mouse PSMA Mouse Inquiry
KN-0422-LN5 Recombinant Humanized Anti-CD3 x Anti-PSMA Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Chimeric; Humanized PSMA Chimeric; Humanized Inquiry
SCIGG-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (scIgG) Human Single chain IgGs CD3 Human PSMA Human Inquiry
FABVC-387 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Fab-sdAb-Fc) Human Fab-scFv/sdAb-Fc CD3 Mouse PSMA llama Inquiry
BSSG-387 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (sdAb-IgG) Human sdAb-IgG CD3 Mouse PSMA llama Inquiry
HCAB-032 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (sdAb-Fc-sdAb) Human sdAb-Fc-sdAb CD3 llama PSMA llama Inquiry
BIBD-387 Recombinant Anti-CD3 x Anti-PSMA VHH BispecificAntibody (Bibody) Human Bibody CD3 Mouse PSMA llama Inquiry
IGVHH-032 Recombinant Anti-CD3 x Anti-PSMA sdAb Bispecific Antibody (IgG-sdAb) Human IgG-sdAb CD3 Mouse PSMA llama Inquiry
BIVHH-032 Recombinant Anti-CD3 sdAb x Anti-PSMA sdAb Bispecific Antibody (Bi-sdAb) Human Bi-sdAb CD3 llama PSMA llama Inquiry
SCIGG-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (scIgG) Human Single chain IgGs CD3 Mouse PSMA Mouse Inquiry
FVTIG-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD3 Human PSMA Human Inquiry
FVTIG-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD3 Mouse PSMA Mouse Inquiry
BSSG-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (scFv-IgG) Human scFv-IgG CD3 Human PSMA Human Inquiry
BSSG-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (scFv-IgG) Human scFv-IgG CD3 Mouse PSMA Mouse Inquiry
IGLFV-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD3 Human PSMA Human Inquiry
IGLFV-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD3 Mouse PSMA Mouse Inquiry
BSGV-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (IgG-Fv) Human IgG-Fv CD3 Mouse PSMA Mouse Inquiry
BSGV-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (IgG-Fv) Human IgG-Fv CD3 Mouse PSMA Mouse Inquiry
BSDG-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (Fv-IgG) Human Fv-IgG CD3 Human PSMA Human Inquiry
BSDG-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Fv-IgG) Human Fv-IgG CD3 Mouse PSMA Mouse Inquiry
BABFV-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD3 Human PSMA Human Inquiry
BABFV-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD3 Mouse PSMA Mouse Inquiry
FABVC-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD3 Human PSMA Human Inquiry
FABVC-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD3 Mouse PSMA Mouse Inquiry
SCDBC-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD3 Human PSMA Human Inquiry
SCDBC-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD3 Mouse PSMA Mouse Inquiry
BSDBC-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD3 Human PSMA Human Inquiry
BSDBC-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD3 Mouse PSMA Mouse Inquiry
SCDBF-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD3 Human PSMA Human Inquiry
SCDBF-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD3 Mouse PSMA Mouse Inquiry
BSFVF-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD3 Human PSMA Human Inquiry
BSFVF-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD3 Mouse PSMA Mouse Inquiry
BSDBF-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD3 Human PSMA Human Inquiry
BSDBF-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD3 Mouse PSMA Mouse Inquiry
BSTF-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD3 Mouse PSMA Mouse Inquiry
BSTF-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD3 Mouse PSMA Mouse Inquiry
BSCFV-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (scFv-Fc) Human scFv-Fc CD3 Mouse PSMA Mouse Inquiry
BSCFV-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (scFv-Fc) Human scFv-Fc CD3 Mouse PSMA Mouse Inquiry
MNAB-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (Miniantibody) Human Miniantibody CD3 Mouse PSMA Mouse Inquiry
MNAB-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Miniantibody) Human Miniantibody CD3 Mouse PSMA Mouse Inquiry
BSFC-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD3 Mouse PSMA Mouse Inquiry
BSFC-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD3 Mouse PSMA Mouse Inquiry
BSCC-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD3 Mouse PSMA Mouse Inquiry
BSCC-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD3 Mouse PSMA Mouse Inquiry
BIBD-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (Bibody) Human Bibody CD3 Mouse PSMA Mouse Inquiry
BIBD-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Bibody) Human Bibody CD3 Mouse PSMA Mouse Inquiry
FABFV-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Human PSMA Human Inquiry
FABFV-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse PSMA Mouse Inquiry
MiniB-H278 Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (Minibody) Human Minibody CD3 Human PSMA Human Inquiry
MiniB-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Minibody) Human Minibody CD3 Mouse PSMA Mouse Inquiry
SCTB-H171 Recombinant Human Anti-PSMA x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Human PSMA Human Inquiry
SCDB-H276 Recombinant Human Anti-CD3 x Anti-PSMA Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Human PSMA Human Inquiry
FABIG-H276 Recombinant Human Anti-CD3 x Anti-PSMA Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Human PSMA Human Inquiry
TRIB-H278 Recombinant Human Anti-CD3 x Anti-PSMA Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Human PSMA Human Inquiry
BSIG-H276 Human Anti-CD3 x Anti-PSMA Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Human PSMA Human Inquiry
CROSSAB-H276 Recombinant Human Anti-CD3 x Anti-PSMA Bispecific Antibody (CrossMab) Human CrossMab CD3 Human PSMA Human Inquiry
IGFV-H276 Recombinant Human Anti-CD3 x Anti-PSMA Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Human PSMA Human Inquiry
BSDB-H276 Recombinant Human Anti-CD3 x Anti-PSMA Bispecific Antibody (Diabody) Human Diabody CD3 Human PSMA Human Inquiry
BSFAB-H276 Recombinant Human Anti-CD3 x Anti-PSMA Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Human PSMA Human Inquiry
BSFV-H276 Recombinant Human Anti-CD3 x Anti-PSMA Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Human PSMA Human Inquiry
SCTB-075 Recombinant Anti-PSMA x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Mouse PSMA Mouse Inquiry
SCDB-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Mouse PSMA Mouse Inquiry
FABIG-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Mouse PSMA Mouse Inquiry
TRIB-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Mouse PSMA Mouse Inquiry
BSIG-102 Anti-CD3 x Anti-PSMA Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Mouse PSMA Mouse Inquiry
CROSSAB-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (CrossMab) Human CrossMab CD3 Mouse PSMA Mouse Inquiry
IGFV-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Mouse PSMA Mouse Inquiry
BSDB-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Diabody) Human Diabody CD3 Mouse PSMA Mouse Inquiry
BSFAB-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse PSMA Mouse Inquiry
BSFV-102 Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse PSMA Mouse Inquiry

Background

PSMA, full name as prostate-specific membrane antigen, is a member of the M28 peptidase family and a 100kDa type II transmembrane glycoprotein, serving as a multifaceted glutamate carboxypeptidase with diverse alternative substrates. This protein exhibits high expression levels in both primary and metastatic prostate cancer, with comparatively lower expression in normal prostate tissue. PSMA's presence may confer a survival advantage to tumors under conditions of cellular stress. Beyond prostate cancer, PSMA has been identified in the tumor vascular endothelium of various cancers and is detected at lower levels in particular normal tissues, including certain proximal renal tubules and duodenal mucosa. Notably, PSMA immunoreactivity ranges from absent to moderate in most hyperplastic and benign tissues.

Elucidating the cellular function of PSMA in prostate cancer cells: insights from established in vitro studies. (Saeki, et al., 2010)Fig.1 Elucidating the cellular function of PSMA in prostate cancer cells: insights from established in vitro studies.1

Reference

  1. Sheehan, Beshara, et al. "Prostate-specific membrane antigen biology in lethal prostate cancer and its therapeutic implications." European urology focus 8.5 (2022): 1157-1168.
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