Overview

Apoptosis, a regulated form of cell death, is a fundamental mechanism observed in multicellular organisms. Apoptosis plays an important role in many biological processes, such as immune system homeostasis, and hormone-driven atrophy. Comprehending the underlying mechanism of apoptosis holds significant importance, as it assumes a central role in the therapeutic management of cancer and various other ailments. Consequently, the screening and profiling of apoptosis-related pathways has profound significance for the development of drugs targeting apoptosis-related proteins.

Fig.1 Apoptosis pathways.1Fig. 1 Apoptosis pathways. (Chaudhry, et al., 2022)

Our Apoptosis Screening & Profiling Service

With years of experience and expertise in apoptosis signal pathways, Creative Biolabs succeeds in providing global customers with comprehensive apoptosis screening & profiling services. We have several detection methods to perform apoptosis screening & profiling, one of which is by measuring the fluorescence signal after incubation with an apoptosis target bound to its ligand. Meanwhile, we offer a variety of apoptosis targets-related services to empower customers' drug discovery programs. The amalgamation of our specialist team and extensive range of services ensures that we deliver high-quality data with expeditious turnaround time.

Fig.2 The bioluminescent annexin assay concept. 2Fig. 2 The bioluminescent annexin assay concept. (Kupcho, et al., 2019)

The Breadth of Our Apoptosis Screening & Profiling Service

Fig.5 Fig. 3 The breadth of our apoptosis screening & profiling service. (Creative Biolabs Original)

Work with Creative Biolabs

Fig.4 Contact Flowchart. Fig. 6 Work with Creative Biolabs. (Creative Biolabs Original)

Creative Biolabs provides best-in-class service that allows for full customization and design from pilot studies to special targeted projects, meaning the service is specifically tailored to answer customers' biological questions. Our competent team, together with our diverse service portfolio, gives us confidence in providing high-quality data in a timely manner.

For more details on our apoptosis screening & profiling service, please feel free to contact us. We are pleased to work together with global customers' attractive projects.

References

  1. Chaudhry, Gul-e-Saba, et al. "Cancer and apoptosis: The apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeutics." Frontiers in Pharmacology 13 (2022): 842376.
    Distributed under Open Access License CC BY 4.0, without modification.
  2. Kupcho, Kevin, et al. "A real-time, bioluminescent annexin V assay for the assessment of apoptosis." Apoptosis 24 (2019): 184-197.
    Distributed under Open Access License CC BY 4.0, without modification.

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