As a well-recognized services and products provider in antibody discovery and development, Creative Biolabs has always been striving to explore more efficient and convenient solutions to best deliver custom objectives. Here, we are proud to present our well-tailored premade rodent antibody libraries for anti-membrane protein antibody discovery to our worldwide customers.
As one of the most powerful strategies, phage display technology, which can create a comprehensive candidate pool to isolate optimal binders via high-throughput screening, is widely applied for developing antibodies against a variety of targets. The vital part of phage display lies in constructing a library with adequate size & capacity, which is the prerequisite for successful antibody screenings. However, in case of membrane targets that are very difficult to prepare, immunization can be quite time- and labor-consuming, especially many human proteins are highly homologous to rodent one. A promising alternative is to premade library screening approach, which directly bypasses the tedious immunization & library construction steps, thus can be very fast and convenient.
Currently, Creative Biolabs presents many ready-to-use premade antibody libraries (in scFv/Fab format) from non-immunized mice/rats. Based on strict QC steps, these libraries guarantee sufficient capacity and diversity capable of deriving high-specificity, high-affinity binders against many membrane targets:
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Highlight advantages of premade human antibody library screening for anti-membrane protein antibody discovery:
Creative Biolabs is professional in tailoring highly specific, highly affinitive antibodies targeting various membrane proteins. Our ready-to-use premade libraries cover many species (human, mouse, rat, chicken, camel, etc.) and formats (scFv, Fab, VHH), based on non-immune hosts or synthetic approaches. Besides, one-stop membrane protein immunogen preparation service is also available upon request, with multiple options (e.g. liposomes, micelles, nanodiscs, whole cells, etc.). Our technique staff has extensive expertise in dealing with various GPCR immunogens, ion channel immunogens, and transporter immunogens. Please feel free to contact us for more details.