This product is a RPMI 1788 B cell engineering tool based on the Gold nanoparticles (Transferrin/Transferrin receptor) delivery system and CRISPR-based (CCR5-crispr RNA-SpCas9-Nocodazole) genome editor.
| Host Cell | RPMI 1788 |
| Target | NEUROG2 |
| Insert Clone | 15HCLCCR |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | Nocodazole |
| Targeting Strategy | pH-dependent |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | Transferrin/Transferrin receptor |
| Active Agents | Bortezomib |
| Particle Size | <500 |
| Charge (mv) | 10 to 100 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Lung cancer; Colorectal cancer |
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