This product is a Ramos.2G6.4C10 B cell engineering tool based on the Magnetic nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (AAVS1-huIgH296-Cpf1-Nocodazole) genome editor.
| Host Cell | Ramos.2G6.4C10 |
| Target | NEUROG2 |
| Insert Clone | BCGW-1344CR |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | huIgH296 |
| Nuclease | Cpf1 |
| Enhancer | Nocodazole |
| Targeting Strategy | pH responsive, time-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Magnetic nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Talazoparib, temozolomide |
| Particle Size | 10-1000 |
| Charge (mv) | ≤50 |
| Total Atom Count | -70000000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | Adenoviruses |
| Vector Name | BCpCDH3 |
| Targeting Diseases | Breast cancer; Lung cancer; Colorectal cancer |
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