This product is a BC-2 B cell engineering tool based on the Liposomes (Hyaluronic acid/ RHAMM, CD44) delivery system and CRISPR-based (hROSA26-SpCas9-SpCas9-Brefeldin A) genome editor.
| Host Cell | BC-2 |
| Target | NEUROG2 |
| Insert Clone | 3D8CR |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | SpCas9 |
| Nuclease | SpCas9 |
| Enhancer | Brefeldin A |
| Targeting Strategy | pH responsive |
| Insertion sites | Large DNA sequences |
| Vehicles | Liposomes |
| Ligand/Receptor | Hyaluronic acid/ RHAMM, CD44 |
| Active Agents | DOX |
| Particle Size | 1-100 |
| Charge (mv) | 10 to 35 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | Adenoviruses |
| Vector Name | BCpCDH3 |
| Targeting Diseases | Breast cancer; Lung cancer; Colorectal cancer |
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