This product is a Raji-Luc2 B cell engineering tool based on the Nanoparticles (EpCAM aptamer/Epithelial celladhesion molecule) delivery system and CRISPR-based (CCR5-crispr RNA-SpCas9-RS-1) genome editor.
| Host Cell | Raji-Luc2 |
| Target | NEUROG3 |
| Insert Clone | 1E3CR |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | pH-dependent |
| Insertion sites | Mouse genome E-7 |
| Vehicles | Nanoparticles |
| Ligand/Receptor | EpCAM aptamer/Epithelial cell adhesion molecule |
| Active Agents | ESC8 |
| Particle Size | <500 |
| Charge (mv) | <-1 |
| Total Atom Count | -70000000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Lung cancer; Breast cancer; Prostate cancer; Melanoma |
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