Cas No.: 91990-88-4
PRODUCT INFORMATION
Description
This is a heterobifunctional, photo-reactive crosslinker for photoaffinity labeling. It features an amine-reactive N-hydroxysuccinimide (NHS) ester and a photo-activatable benzophenone group. In a two-step application, the NHS ester first reacts with a primary amine on a 'bait' molecule (e.g., a ligand) in the dark. This probe is then incubated with its 'prey' target. Upon activation with long-wave UV light (approx. 350 nm), the benzophenone group non-selectively inserts into nearby C-H bonds, forming a stable, covalent crosslink to permanently capture transient molecular interactions.
Molecular Weight
323.30
Purity
>98.0%
Formula
C₁₈H₁₃NO₅
Product Type
Heterobifunctional Crosslinkers ; Photo-reactive Crosslinkers
Group 1
NHS
Group 2
Other
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, 2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use
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