N-Succinimidyl 4-Benzoylbenzoate Photo-reactive Crosslinker (CAT#: OLY-1023-YS30)

Description

This is a heterobifunctional, photo-reactive crosslinker for photoaffinity labeling. It features an amine-reactive N-hydroxysuccinimide (NHS) ester and a photo-activatable benzophenone group. In a two-step application, the NHS ester first reacts with a primary amine on a 'bait' molecule (e.g., a ligand) in the dark. This probe is then incubated with its 'prey' target. Upon activation with long-wave UV light (approx. 350 nm), the benzophenone group non-selectively inserts into nearby C-H bonds, forming a stable, covalent crosslink to permanently capture transient molecular interactions.

Molecular Weight

323.30

Purity

>98.0%

Formula

C₁₈H₁₃NO₅

Product Type

Heterobifunctional Crosslinkers ; Photo-reactive Crosslinkers

Group 1

NHS

Group 2

Other

Form (20 deg.C)

Solid

Storage Condition

Store under inert gas, 2-8°C

Molecular Structure