Cas No.: 2579693-28-8
PRODUCT INFORMATION
Description
This is a monofunctional, thiol-reactive PEGylation reagent. It features a very long, 24-unit polyethylene glycol (PEG) chain, capped at one end with an inert methoxy (m) group and functionalized at the other with a sulfhydryl-reactive maleimide. The maleimide group reacts specifically with thiols (cysteines) at pH 6.5-7.5. This reagent is primarily used to attach a large, hydrophilic PEG shield to proteins or peptides (a process called "PEGylation") to improve their in vivo stability, increase half-life, and reduce immunogenicity.
Molecular Weight
1239.45
Purity
>93.0%
Formula
C₅₆H₁₀₆N₂O₂₇
Product Type
PEGylation Reagents
Group 1
Maleimide
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, -20°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- Ethyl 6-[(2-Cyanoethoxy)(4,4-diphenylcyclohexyloxy)phosphoryloxy]hexanoate Albumin Binding Conjugation Reagent (CAT#: OLY-1023-YS182)
- N-Succinimidyl Methacrylate Heterobifunctional Crosslinker (CAT#: OLY-1023-YS25)
- Z-6-Aminohexanoic Acid Heterobifunctional Crosslinker (CAT#: OLY-1023-YS3)
- CPO-PFP Selective N-Terminal Cysteine Residue Crosslinker (CAT#: OLY-1023-YS4)
- N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate (SMCC) Heterobifunctional Crosslinker (CAT#: OLY-1023-YS29)
- SANPAH (CAT#: OLY-1023-YS68)
- Genipin (CAT#: OLY-1023-YS46)
- Mal-PEG2-CH2CH2Mal PEGylation Crosslinker (CAT#: OLY-1023-YS125)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.