Cas No.: 2579693-28-8
PRODUCT INFORMATION
Description
This is a monofunctional, thiol-reactive PEGylation reagent. It features a very long, 24-unit polyethylene glycol (PEG) chain, capped at one end with an inert methoxy (m) group and functionalized at the other with a sulfhydryl-reactive maleimide. The maleimide group reacts specifically with thiols (cysteines) at pH 6.5-7.5. This reagent is primarily used to attach a large, hydrophilic PEG shield to proteins or peptides (a process called "PEGylation") to improve their in vivo stability, increase half-life, and reduce immunogenicity.
Molecular Weight
1239.45
Purity
>93.0%
Formula
C₅₆H₁₀₆N₂O₂₇
Product Type
PEGylation Reagents
Group 1
Maleimide
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, -20°C
Molecular Structure
For Research Use Only | Not For Clinical Use
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