N-(2-Aminoethyl)maleimide Hydrochloride Heterobifunctional Crosslinker (CAT#: OLY-1023-YS90)
Datasheet MSDSCas No.: 134272-64-3
PRODUCT INFORMATION
Description
This is a heterobifunctional crosslinker with a short spacer. It features a sulfhydryl-reactive maleimide group and a primary amine (as an HCl salt for stability and solubility). The maleimide group specifically targets thiols (cysteines) at pH 6.5-7.5 to form a stable thioether bond. The primary amine can be reacted with various electrophiles, such as NHS esters or isothiocyanates. This linker is commonly used to add a free amine handle to a cysteine-containing peptide or protein, or to conjugate a thiol-containing molecule to an amine-reactive surface.
Molecular Weight
176.60
Purity
>93.0%
Formula
C₆H₈N₂O₂·HCl
Product Type
Heterobifunctional Crosslinkers
Group 1
Maleimide
Group 2
NH₂
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, 2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use
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