Home > Products > Ad Fiber Knob & ITGAV > Recombinant Anti-Ad Fiber Knob x Anti-ITGAV Bispecific Antibody (Tandem Diabody)

Recombinant Anti-Ad Fiber Knob x Anti-ITGAV Bispecific Antibody (Tandem Diabody)  (CAT#: T-BSDB-005)

Recombinant Anti-Ad fiber knob x Anti-ITGAV Bispecific Antibody (Tandem Diabody) is designed to be expressed as a monomeric subunit (single chain Diabody, scDb), with four variable domains from two parental antibodies. Then the two peptide chains can dimerize in a head-to-tail fashion. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.
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Specifications

Targets
Ad Fiber Knob & ITGAV
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Colorectal cancer (CRC); Prostate cancer; Ovarian cancer

Targets

Target 1
Ad Fiber Knob
Alternative Names
Ad fiber knob; Adenovirus fiber knob; adenovirus fiber protein; knob domain of Ad fiber
Target 2
ITGAV
Gene ID
UniProt ID
Alternative Names
ITGAV; integrin, alpha V; CD51; MSK8; VNRA; VTNR; integrin alpha-V; integrin alphaVbeta3; vitronectin receptor subunit alpha; antigen identified by monoclonal antibody L230; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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