Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Fab-scFv-Fc) (FABVC-013)

Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-B cell lymphoma 38C13 Idiotype antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-CD44 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.

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Specifications

Targets

B cell lymphoma 38C13 Idiotype & CD44

Type

Fab-Fc Fusion Proteins

Species Reactivity

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

B cell lymphoma

Targets

Target 1

B cell lymphoma 38C13 Idiotype

Alternative Names

B cell lymphoma 38C13 Idiotype; B cell lymphoma; 38C13; Idiotype; Id

Target 2

CD44

Gene ID

12505

UniProt ID

P15379

Alternative Names

CD44; CD44 antigen; ECMRIII; Extracellular matrix receptor III; HCAM; Homing cell adhesion molecule; Pgp-1; phagocytic glycoprotein-1; HUTCH-1; Ly-24; Pgp-1; HERMES; AU023126; AW121933; AW146109

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-013)

Specifications

Targets

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