Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-B cell lymphoma 38C13 Idiotype/CD44 tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.
Specifications
Targets
B cell lymphoma 38C13 Idiotype & CD44
Type
Constant Domain-extended Bispecific Fragments
Target 1
B cell lymphoma 38C13 Idiotype
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma
Targets
Target 1
B cell lymphoma 38C13 Idiotype
Alternative Names
B cell lymphoma 38C13 Idiotype; B cell lymphoma; 38C13; Idiotype; Id
Alternative Names
CD44; CD44 antigen; ECMRIII; Extracellular matrix receptor III; HCAM; Homing cell adhesion molecule; Pgp-1; phagocytic glycoprotein-1; HUTCH-1; Ly-24; Pgp-1; HERMES; AU023126; AW121933; AW146109
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