Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-B cell lymphoma 38C13 Idiotype specificity or anti-CD44 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.
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