Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-B cell lymphoma 38C13 Idiotype specificity or anti-CD44 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.
Specifications
Targets
B cell lymphoma 38C13 Idiotype & CD44
Target 1
B cell lymphoma 38C13 Idiotype
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma
Targets
Target 1
B cell lymphoma 38C13 Idiotype
Alternative Names
B cell lymphoma 38C13 Idiotype; B cell lymphoma; 38C13 ; Idiotype; Id
Alternative Names
CD44; CD44 antigen; ECMRIII; Extracellular matrix receptor III; HCAM; Homing cell adhesion molecule; Pgp-1; phagocytic glycoprotein-1; HUTCH-1; Ly-24; Pgp-1; HERMES; AU023126; AW121933; AW146109
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