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Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (scFv-IgG) (CAT#: BSSG-114)
Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD33 antibody variable domain are respectively connected to the N terminus of the anti-CD16 IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Acute myeloid leukemia (AML); Ulcerative Colitis (UC); Myelodysplastic syndromes (MDS); Gastric cancer therapy.
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