Recombinant Human Anti-CD89 x Human Anti-HIV-1 gp41 Bispecific Antibody (Minibody) (MiniB-H306)

Recombinant Anti-CD89 x Anti-HIV-1 gp41 Bispecific Antibody (Minibody) is designed to be expressed as the anti-CD89 scFv fused to N-terminus of Knob-CH3 domain and the anti-HIV-1 gp41 scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can retarget macrophages to tumor cells. It is designed for the research of HIV-1 infection, AIDS therapy.

Datasheet INQUIRY

Specifications

Targets

CD89 & HIV-1 gp41

Type

Minibody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

HIV-1 infection, AIDS

Targets

Target 1

CD89

Gene ID

2204

UniProt ID

P24071

Alternative Names

FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor

Target 2

HIV-1 gp41

Gene ID

155971

UniProt ID

Q0H5Z9

Alternative Names

ENV; gp160; Envelope glycoprotein 120; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain; human immunodeficiency virus type 1; human immunodeficiency virus type 1 gp120; human immunodeficiency virus type 1 glycoprotein 120; gp41; GP41; glycoprotein 41

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD89 x Human Anti-HIV-1 gp41 Bispecific Antibody (Minibody) (CAT#: MiniB-H306)

Specifications

Targets

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