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Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-154)
Recombinant Anti-EGFR x Anti-MET Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-EGFR antibody are fused to the C terminus of an anti-MET IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Colorectal cancer; Pancreatic cancer; Head and neck cancer; Non-small cell lung cancer (NSCLC) therapy.
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