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Recombinant Human Anti-NkG2A x Mouse Anti-CD30 Bispecific Antibody (Tandem Fab)  (CAT#: KN-0725-N87)

Recombinant Human Anti-NkG2A x Mouse Anti-CD30 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-NkG2A and anti-CD30 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL) therapy.
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Specifications

Targets
NkG2A & CD30
Type
Tandem Fab
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL)
Host Animal 1
Human
Host Animal 2
Mouse

Targets

Target 1
NkG2A
Gene ID
UniProt ID
Alternative Names
Killer cell lectin-like receptor subfamily C member 1; KLRC1; CD159 antigen-like family member A; NKG2-A; NKG2-1; NK group 2 member A; KLR family member C1; NK cell inhibitory receptor for HLA-E; NKG2; NKG2A; CD159A; killer cell lectin like receptor C1; NKG2-A/NKG2-B type II integral membrane protein; CD159 antigen-like family member A; NK cell receptor A; NKG2-A/B-activating NK receptor; CD159a
Target 2
CD30
Gene ID
UniProt ID
Alternative Names
TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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