Name: Recombinant Human Anti-NkG2D x Mouse Anti-GPC3 Bispecific Antibody (scFv-Fc)
SKU: KN-0725-N48
Rating: 5 (1 reviews)

Recombinant Human Anti-NkG2D x Mouse Anti-GPC3 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-NkG2D specificity or anti-GPC3 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Hepatocellular cancer (HCC); Melanoma therapy.

Datasheet INQUIRY

Specifications

Targets

NkG2D & GPC3

Type

scFv-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer (HCC); Melanoma

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

NkG2D

Gene ID

22914

UniProt ID

P26718

Alternative Names

CD314; Cluster of Differentiation 314; KLRK1; Killer cell lectin-like receptor subfamily K member 1; NKG2-D; NK cell activating receptor NKG2D; Natural killer group 2D; KLR; NKG2D; D12S2489E; killer cell lectin like receptor K1; NKG2-D type II integral membrane protein; NK cell receptor D; NKG2-D-activating NK receptor

Target 2

GPC3

Gene ID

2719

UniProt ID

P51654

Alternative Names

SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; GPC3; glypican 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-NkG2D x Mouse Anti-GPC3 Bispecific Antibody (scFv-Fc) (CAT#: KN-0725-N48)

Specifications

Targets

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