Recombinant Anti-PcrV x Anti-PsI Bispecific Antibody (Fab-scFv-Fc) (FABVC-184)

Recombinant Anti-PcrV x Anti-PsI Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-PcrV antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-PsI to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can bind and inactivate two antigens simultaneously. It is designed for the research of Pneumonia therapy.

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Specifications

Targets

PcrV & PsI

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Pneumonia

Targets

Target 1

PcrV

Alternative Names

pcrV; Type III secretion protein PcrV; Pseudomonas aeruginosa

Target 2

PsI

Alternative Names

Psl; Pseudomonas aeruginosa exopolysaccharide

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-PcrV x Anti-PsI Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-184)

Specifications

Targets

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