Recombinant Anti-PcrV x Anti-PsI Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-PcrV antibody variable domain is fused to the C terminal of an IgG of anti-PsI antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb can bind and inactivate two antigens simultaneously. It is designed for the research of Pneumonia therapy.
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