Home > Products > PcrV & PsI > Recombinant Anti-PcrV x Anti-PsI Bispecific Antibody (scFv-IgG)

Recombinant Anti-PcrV x Anti-PsI Bispecific Antibody (scFv-IgG)  (BSSG-184)

Recombinant Anti-PcrV x Anti-PsI Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-PcrV antibody variable domain are respectively connected to the N terminus of the anti-PsI IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can bind and inactivate two antigens simultaneously. It is designed for the research of Pneumonia therapy.

Specifications

Targets
PcrV & PsI
Type
Appended IgGs
Species Reactivity
Human
Target 1
PcrV
Host Animal 1
Mouse
Target 2
PsI
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Pneumonia

Targets

Target 1
PcrV
Alternative Names
pcrV; Type III secretion protein PcrV; Pseudomonas aeruginosa
Target 2
PsI
Alternative Names
Psl; Pseudomonas aeruginosa exopolysaccharide

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