Recombinant Anti-PcrV x Anti-PsI Bispecific Antibody (scFv-Fc-scFv) (BSTF-184)

Recombinant Anti-PcrV x Anti-PsI Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-PcrV scFv is fused to the N-terminus of Fc via a hinge region while another anti-PsI scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can bind and inactivate two antigens simultaneously. It is designed for the research of Pneumonia therapy.

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Specifications

Targets

PcrV & PsI

Type

scFv-Fc-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Pneumonia

Targets

Target 1

PcrV

Alternative Names

pcrV; Type III secretion protein PcrV; Pseudomonas aeruginosa

Target 2

PsI

Alternative Names

Psl; Pseudomonas aeruginosa exopolysaccharide

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-PcrV x Anti-PsI Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-184)

Specifications

Targets

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