Recombinant Human Anti-VEGFR2 x Human Anti-VEGFR3 Bispecific Antibody (scFv-CH3) (BSFC-H353)

Recombinant Anti-VEGFR2 x Anti-VEGFR3 Bispecific Antibody (scFv-CH3) contains two chains. The anti-VEGFR2 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-VEGFR3 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can block two receptors simultaneously. It is designed for the research of Cancers therapy.

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Specifications

Targets

VEGFR2 & VEGFR3

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Targets

Target 1

VEGFR2

Gene ID

3791

UniProt ID

A0A024RD88

Alternative Names

FLK1; CD309; VEGFR; VEGFR2; Vascular endothelial growth factor receptor 2; Kinase insert domain receptor; Fetal liver kinase 1; Kinase insert domain receptor, a type III receptor; KDR

Target 2

VEGFR3

Gene ID

2324

UniProt ID

P35916

Alternative Names

FLT4; PCL; FLT-4; FLT41; LMPH1A; VEGFR3; VEGFR-3; fms related tyrosine kinase 4; Vascular endothelial growth factor 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-VEGFR2 x Human Anti-VEGFR3 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-H353)

Specifications

Targets

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