Recombinant Anti-VEGFR2 x Anti-VEGFR3 Bispecific Antibody (Diabody-Fc) (BSDBF-191)

Recombinant Anti-VEGFR2 x Anti-VEGFR3 Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-VEGFR2 and anti-VEGFR3 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can block two receptors simultaneously. It is designed for the research of Cancers therapy.

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Specifications

Targets

VEGFR2 & VEGFR3

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Targets

Target 1

VEGFR2

Gene ID

3791

UniProt ID

A0A024RD88

Alternative Names

FLK1; CD309; VEGFR; VEGFR2; Vascular endothelial growth factor receptor 2; Kinase insert domain receptor; Fetal liver kinase 1; Kinase insert domain receptor, a type III receptor; KDR

Target 2

VEGFR3

Gene ID

2324

UniProt ID

P35916

Alternative Names

FLT4; PCL; FLT-4; FLT41; LMPH1A; VEGFR3; VEGFR-3; fms related tyrosine kinase 4; Vascular endothelial growth factor 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-VEGFR2 x Anti-VEGFR3 Bispecific Antibody (Diabody-Fc) (CAT#: BSDBF-191)

Specifications

Targets

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