Home > Products > VEGFR2 & VEGFR3 > Recombinant Anti-VEGFR2 x Anti-VEGFR3 Bispecific Antibody (scFv4-Ig)

Recombinant Anti-VEGFR2 x Anti-VEGFR3 Bispecific Antibody (scFv4-Ig)  (FVTIG-191)

Recombinant Anti-VEGFR2 x Anti-VEGFR3 Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-VEGFR2 scFv is fused to the CH1 domain of a heavy chain and another anti-VEGFR3 scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can block two receptors simultaneously. It is designed for the research of Cancers therapy.

Specifications

Targets
VEGFR2 & VEGFR3
Type
Appended IgGs
Species Reactivity
Human
Target 1
VEGFR2
Host Animal 1
Mouse
Target 2
VEGFR3
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Cancers

Targets

Target 1
VEGFR2
Gene ID
UniProt ID
Alternative Names
FLK1; CD309; VEGFR; VEGFR2; Vascular endothelial growth factor receptor 2; Kinase insert domain receptor; Fetal liver kinase 1; Kinase insert domain receptor, a type III receptor; KDR
Target 2
VEGFR3
Gene ID
UniProt ID
Alternative Names
FLT4; PCL; FLT-4; FLT41; LMPH1A; VEGFR3; VEGFR-3; fms related tyrosine kinase 4; Vascular endothelial growth factor 3

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