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CD33 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
FABFV-H290 Recombinant Human Anti-CD33 x Human Anti-CD16 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD33 Human CD16 Human Inquiry
FABFV-H242 Recombinant Human Anti-CD3 x Human Anti-CD33 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Human CD33 Human Inquiry
FABFV-116 Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (Fab-Fv) Human Fab-Fv CD33 Mouse DENV Mouse Inquiry
FABFV-115 Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD33 Mouse CD64 Mouse Inquiry
FABFV-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD33 Mouse CD16 Mouse Inquiry
FABFV-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD33 Mouse Inquiry
MiniB-H292 Recombinant Human Anti-CD33 x Human Anti-DENV Bispecific Antibody (Minibody) Human Minibody CD33 Human DENV Human Inquiry
MiniB-H291 Recombinant Human Anti-CD33 x Human Anti-CD64 Bispecific Antibody (Minibody) Human Minibody CD33 Human CD64 Human Inquiry
MiniB-H290 Recombinant Human Anti-CD33 x Human Anti-CD16 Bispecific Antibody (Minibody) Human Minibody CD33 Human CD16 Human Inquiry
MiniB-H242 Recombinant Human Anti-CD3 x Human Anti-CD33 Bispecific Antibody (Minibody) Human Minibody CD3 Human CD33 Human Inquiry
MiniB-116 Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (Minibody) Human Minibody CD33 Mouse DENV Mouse Inquiry
MiniB-115 Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Minibody) Human Minibody CD33 Mouse CD64 Mouse Inquiry
MiniB-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Minibody) Human Minibody CD33 Mouse CD16 Mouse Inquiry
MiniB-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Minibody) Human Minibody CD3 Mouse CD33 Mouse Inquiry
SCTB-H197 Recombinant Human Anti-CD33 x Anti-CD16 x Anti-CD19 Trispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD33 Human CD16 Human Inquiry
SCTB-H196 Recombinant Human Anti-CD33 x Anti-CD16 x CD123 Trispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD33 Human CD16 Human Inquiry
SCTB-H182 Recombinant Human Anti-CD33 x Anti-CD64 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD33 Human CD64 Human Inquiry
SCTB-H181 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD33 Human CD16 Human Inquiry
SCTB-H136 Recombinant Human Anti-CD33 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Human CD33 Human Inquiry
SCDB-H290 Recombinant Human Anti-CD33 x Anti-DENV Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD33 Human DENV Human Inquiry
SCDB-H289 Recombinant Human Anti-CD33 x Anti-CD64 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD33 Human CD64 Human Inquiry
SCDB-H288 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD33 Human CD16 Human Inquiry
SCDB-H240 Recombinant Human Anti-CD3 x Anti-CD33 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Human CD33 Human Inquiry
FABIG-H290 Recombinant Human Anti-CD33 x Anti-DENV Bispecific Antibody (Fab-IgG) Human Fab-IgG CD33 Human DENV Human Inquiry
FABIG-H289 Recombinant Human Anti-CD33 x Anti-CD64 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD33 Human CD64 Human Inquiry
FABIG-H288 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD33 Human CD16 Human Inquiry
FABIG-H240 Recombinant Human Anti-CD3 x Anti-CD33 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Human CD33 Human Inquiry
TRIB-H354 Recombinant Human Anti-CD16 x Anti-CD33 x Anti-CD19 Trispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD16 Human CD33 Human Inquiry
TRIB-H353 Recombinant Human Anti-CD16 x Anti-CD33 x Anti-CD123 Trispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD16 Human CD33 Human Inquiry
TRIB-H292 Recombinant Human Anti-CD33 x Anti-DENV Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD33 Human DENV Human Inquiry
TRIB-H291 Recombinant Human Anti-CD33 x Anti-CD64 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD33 Human CD64 Human Inquiry
TRIB-H290 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD33 Human CD16 Human Inquiry
TRIB-H242 Recombinant Human Anti-CD3 x Anti-CD33 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Human CD33 Human Inquiry
BSIG-H290 Human Anti-CD33 x Anti-DENV Bispecific Antibody (IgG-IgG) Human IgG-IgG CD33 Human DENV Human Inquiry
BSIG-H289 Human Anti-CD33 x Anti-CD64 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD33 Human CD64 Human Inquiry
BSIG-H288 Human Anti-CD33 x Anti-CD16 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD33 Human CD16 Human Inquiry
BSIG-H240 Human Anti-CD3 x Anti-CD33 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Human CD33 Human Inquiry
CROSSAB-H290 Recombinant Human Anti-CD33 x Anti-DENV Bispecific Antibody (CrossMab) Human CrossMab CD33 Human DENV Human Inquiry
CROSSAB-H289 Recombinant Human Anti-CD33 x Anti-CD64 Bispecific Antibody (CrossMab) Human CrossMab CD33 Human CD64 Human Inquiry
CROSSAB-H288 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (CrossMab) Human CrossMab CD33 Human CD16 Human Inquiry
CROSSAB-H240 Recombinant Human Anti-CD3 x Anti-CD33 Bispecific Antibody (CrossMab) Human CrossMab CD3 Human CD33 Human Inquiry
IGFV-H290 Recombinant Human Anti-CD33 x Anti-DENV Bispecific Antibody (IgG-scFv) Human IgG-scFv CD33 Human DENV Human Inquiry
IGFV-H289 Recombinant Human Anti-CD33 x Anti-CD64 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD33 Human CD64 Human Inquiry
IGFV-H288 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD33 Human CD16 Human Inquiry
IGFV-H240 Recombinant Human Anti-CD3 x Anti-CD33 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Human CD33 Human Inquiry
BSDB-H290 Recombinant Human Anti-CD33 x Anti-DENV Bispecific Antibody (Diabody) Human Diabody CD33 Human DENV Human Inquiry
BSDB-H289 Recombinant Human Anti-CD33 x Anti-CD64 Bispecific Antibody (Diabody) Human Diabody CD33 Human CD64 Human Inquiry
BSDB-H288 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (Diabody) Human Diabody CD33 Human CD16 Human Inquiry
BSDB-H240 Recombinant Human Anti-CD3 x Anti-CD33 Bispecific Antibody (Diabody) Human Diabody CD3 Human CD33 Human Inquiry
BSFAB-H290 Recombinant Human Anti-CD33 x Anti-DENV Bispecific Antibody (Tandem Fab) Human Tandem Fab CD33 Human DENV Human Inquiry
BSFAB-H289 Recombinant Human Anti-CD33 x Anti-CD64 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD33 Human CD64 Human Inquiry
BSFAB-H288 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD33 Human CD16 Human Inquiry
BSFAB-H240 Recombinant Human Anti-CD3 x Anti-CD33 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Human CD33 Human Inquiry
BSFV-H290 Recombinant Human Anti-CD33 x Anti-DENV Bispecific Antibody (Tandem scFv) Human Tandem scFv CD33 Human DENV Human Inquiry
BSFV-H289 Recombinant Human Anti-CD33 x Anti-CD64 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD33 Human CD64 Human Inquiry
BSFV-H288 Recombinant Human Anti-CD33 x Anti-CD16 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD33 Human CD16 Human Inquiry
BSFV-H240 Recombinant Human Anti-CD3 x Anti-CD33 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Human CD33 Human Inquiry
SCTB-105 Recombinant Anti-CD33 x Anti-CD16 x Anti-CD19 Trispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD33 Mouse CD16 Mouse Inquiry
SCTB-104 Recombinant Anti-CD33 x Anti-CD16 x CD123 Trispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD33 Mouse CD16 Mouse Inquiry
SCTB-087 Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD33 Mouse CD64 Mouse Inquiry
SCTB-086 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD33 Mouse CD16 Mouse Inquiry
SCTB-038 Recombinant Anti-CD33 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Mouse CD33 Mouse Inquiry
SCDB-116 Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD33 Mouse DENV Mouse Inquiry
SCDB-115 Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD33 Mouse CD64 Mouse Inquiry
SCDB-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD33 Mouse CD16 Mouse Inquiry
SCDB-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Mouse CD33 Mouse Inquiry
FABIG-116 Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (Fab-IgG) Human Fab-IgG CD33 Mouse DENV Mouse Inquiry
FABIG-115 Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD33 Mouse CD64 Mouse Inquiry
FABIG-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD33 Mouse CD16 Mouse Inquiry
FABIG-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Mouse CD33 Mouse Inquiry
TRIB-193 Recombinant Anti-CD16 x Anti-CD33 x Anti-CD19 Trispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD16 Mouse CD33 Mouse Inquiry
TRIB-192 Recombinant Anti-CD16 x Anti-CD33 x Anti-CD123 Trispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD16 Mouse CD33 Mouse Inquiry
TRIB-116 Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD33 Mouse DENV Mouse Inquiry
TRIB-115 Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD33 Mouse CD64 Mouse Inquiry
TRIB-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD33 Mouse CD16 Mouse Inquiry
TRIB-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Mouse CD33 Mouse Inquiry
BSIG-116 Anti-CD33 x Anti-DENV Bispecific Antibody (IgG-IgG) Human IgG-IgG CD33 Mouse DENV Mouse Inquiry
BSIG-115 Anti-CD33 x Anti-CD64 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD33 Mouse CD64 Mouse Inquiry
BSIG-114 Anti-CD33 x Anti-CD16 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD33 Mouse CD16 Mouse Inquiry
BSIG-066 Anti-CD3 x Anti-CD33 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Mouse CD33 Mouse Inquiry
CROSSAB-116 Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (CrossMab) Human CrossMab CD33 Mouse DENV Mouse Inquiry
CROSSAB-115 Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (CrossMab) Human CrossMab CD33 Mouse CD64 Mouse Inquiry
CROSSAB-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (CrossMab) Human CrossMab CD33 Mouse CD16 Mouse Inquiry
CROSSAB-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (CrossMab) Human CrossMab CD3 Mouse CD33 Mouse Inquiry
IGFV-116 Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (IgG-scFv) Human IgG-scFv CD33 Mouse DENV Mouse Inquiry
IGFV-115 Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD33 Mouse CD64 Mouse Inquiry
IGFV-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD33 Mouse CD16 Mouse Inquiry
IGFV-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Mouse CD33 Mouse Inquiry
BSDB-116 Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (Diabody) Human Diabody CD33 Mouse DENV Mouse Inquiry
BSDB-115 Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Diabody) Human Diabody CD33 Mouse CD64 Mouse Inquiry
BSDB-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Diabody) Human Diabody CD33 Mouse CD16 Mouse Inquiry
BSDB-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Diabody) Human Diabody CD3 Mouse CD33 Mouse Inquiry
BSFAB-116 Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (Tandem Fab) Human Tandem Fab CD33 Mouse DENV Mouse Inquiry
BSFAB-115 Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD33 Mouse CD64 Mouse Inquiry
BSFAB-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD33 Mouse CD16 Mouse Inquiry
BSFAB-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD33 Mouse Inquiry
BSFV-116 Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (Tandem scFv) Human Tandem scFv CD33 Mouse DENV Mouse Inquiry
BSFV-115 Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD33 Mouse CD64 Mouse Inquiry
BSFV-114 Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD33 Mouse CD16 Mouse Inquiry
BSFV-066 Recombinant Anti-CD3 x Anti-CD33 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD33 Mouse Inquiry

Background

The CD33 gene is located on chromosome 19q13.3 and is a member of a class of immune cell surface receptors, known as the Siglecs receptor family of sialic acid-binding immunoglobulin (Ig) like lectins. CD33 is a functionally complex cell surface glycoprotein characterized by Ig-like domains located distal to the V set and proximal to the C2 set of the cell membrane. CD33-related siglecs are mainly expressed in white blood cell subpopulations and are therefore considered to be involved in the regulation of white blood cell function during inflammation and immune responses. The endocytic function of CD33 has been used for targeted cell therapy in acute myeloid leukemia (AML). Another important role of CD33 is its ability to inhibit immune cell function. CD33 has also been reported to regulate cell growth and survival by inhibiting proliferation and inducing cell apoptosis. CD33-related siglecs typically contain one or more immune receptor tyrosine-based inhibitory motifs (ITIM) or ITIM-like motifs at their cytoplasmic tails and can act as inhibitory receptors by inhibiting tyrosine kinase-driven signaling pathways.

Fig.1 Schematic diagram of the proposed pathway of CD33 siglec-mediated suppression of cellular function in Leishmania infection. (Khatua, 2013) Fig.1 Schematic diagram of the proposed pathway of CD33 siglec-mediated suppression of cellular function in Leishmania infection.1

Reference

  1. Khatua, Biswajit, Saptarshi Roy, and Chitra Mandal. "Sialic acids siglec interaction: a unique strategy to circumvent innate immune response by pathogens." The Indian journal of medical research 138.5 (2013): 648.
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