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CD79b Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
BSDG-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Fv-IgG) Human Fv-IgG CD32B Mouse CD79B Mouse Inquiry
BSDG-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Fv-IgG) Human Fv-IgG CD3 Mouse CD79B Mouse Inquiry
BABFV-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD32B Human CD79B Human Inquiry
BABFV-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD3 Human CD79B Human Inquiry
BABFV-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD32B Mouse CD79B Mouse Inquiry
BABFV-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD3 Mouse CD79B Mouse Inquiry
FABVC-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD32B Human CD79B Human Inquiry
FABVC-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD3 Human CD79B Human Inquiry
FABVC-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD32B Mouse CD79B Mouse Inquiry
FABVC-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD3 Mouse CD79B Mouse Inquiry
SCDBC-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD32B Human CD79B Human Inquiry
SCDBC-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD3 Human CD79B Human Inquiry
SCDBC-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD32B Mouse CD79B Mouse Inquiry
SCDBC-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD3 Mouse CD79B Mouse Inquiry
BSDBC-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD32B Human CD79B Human Inquiry
BSDBC-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD3 Human CD79B Human Inquiry
BSDBC-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD32B Mouse CD79B Mouse Inquiry
BSDBC-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD3 Mouse CD79B Mouse Inquiry
SCDBF-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD32B Human CD79B Human Inquiry
SCDBF-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD3 Human CD79B Human Inquiry
SCDBF-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD32B Mouse CD79B Mouse Inquiry
SCDBF-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD3 Mouse CD79B Mouse Inquiry
BSFVF-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD32B Human CD79B Human Inquiry
BSFVF-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD3 Human CD79B Human Inquiry
BSFVF-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD32B Mouse CD79B Mouse Inquiry
BSFVF-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD3 Mouse CD79B Mouse Inquiry
BSDBF-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD32B Human CD79B Human Inquiry
BSDBF-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD3 Human CD79B Human Inquiry
BSDBF-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD32B Mouse CD79B Mouse Inquiry
BSDBF-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD3 Mouse CD79B Mouse Inquiry
BSTF-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD32B Mouse CD79B Mouse Inquiry
BSTF-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD3 Mouse CD79B Mouse Inquiry
BSTF-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD32B Mouse CD79B Mouse Inquiry
BSTF-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD3 Mouse CD79B Mouse Inquiry
BSCFV-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (scFv-Fc) Human scFv-Fc CD32B Mouse CD79B Mouse Inquiry
BSCFV-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (scFv-Fc) Human scFv-Fc CD3 Mouse CD79B Mouse Inquiry
BSCFV-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (scFv-Fc) Human scFv-Fc CD32B Mouse CD79B Mouse Inquiry
BSCFV-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (scFv-Fc) Human scFv-Fc CD3 Mouse CD79B Mouse Inquiry
MNAB-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (Miniantibody) Human Miniantibody CD32B Mouse CD79B Mouse Inquiry
MNAB-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (Miniantibody) Human Miniantibody CD3 Mouse CD79B Mouse Inquiry
MNAB-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Miniantibody) Human Miniantibody CD32B Mouse CD79B Mouse Inquiry
MNAB-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Miniantibody) Human Miniantibody CD3 Mouse CD79B Mouse Inquiry
BSFC-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD32B Mouse CD79B Mouse Inquiry
BSFC-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD3 Mouse CD79B Mouse Inquiry
BSFC-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD32B Mouse CD79B Mouse Inquiry
BSFC-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD3 Mouse CD79B Mouse Inquiry
BSCC-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD32B Mouse CD79B Mouse Inquiry
BSCC-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD3 Mouse CD79B Mouse Inquiry
BSCC-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD32B Mouse CD79B Mouse Inquiry
BSCC-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD3 Mouse CD79B Mouse Inquiry
BIBD-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (Bibody) Human Bibody CD32B Mouse CD79B Mouse Inquiry
BIBD-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (Bibody) Human Bibody CD3 Mouse CD79B Mouse Inquiry
BIBD-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Bibody) Human Bibody CD32B Mouse CD79B Mouse Inquiry
BIBD-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Bibody) Human Bibody CD3 Mouse CD79B Mouse Inquiry
FABFV-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (Fab-Fv) Human Fab-Fv CD32B Human CD79B Human Inquiry
FABFV-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Human CD79B Human Inquiry
FABFV-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Fab-Fv) Human Fab-Fv CD32B Mouse CD79B Mouse Inquiry
FABFV-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD79B Mouse Inquiry
MiniB-H288 Recombinant Human Anti-CD32B x Human Anti-CD79B Bispecific Antibody (Minibody) Human Minibody CD32B Human CD79B Human Inquiry
MiniB-H246 Recombinant Human Anti-CD3 x Human Anti-CD79B Bispecific Antibody (Minibody) Human Minibody CD3 Human CD79B Human Inquiry
MiniB-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Minibody) Human Minibody CD32B Mouse CD79B Mouse Inquiry
MiniB-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Minibody) Human Minibody CD3 Mouse CD79B Mouse Inquiry
SCTB-H140 Recombinant Human Anti-CD79B x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Human CD79B Human Inquiry
SCDB-H286 Recombinant Human Anti-CD32B x Anti-CD79B Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD32B Human CD79B Human Inquiry
SCDB-H244 Recombinant Human Anti-CD3 x Anti-CD79B Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Human CD79B Human Inquiry
FABIG-H286 Recombinant Human Anti-CD32B x Anti-CD79B Bispecific Antibody (Fab-IgG) Human Fab-IgG CD32B Human CD79B Human Inquiry
FABIG-H244 Recombinant Human Anti-CD3 x Anti-CD79B Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Human CD79B Human Inquiry
TRIB-H288 Recombinant Human Anti-CD32B x Anti-CD79B Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD32B Human CD79B Human Inquiry
TRIB-H246 Recombinant Human Anti-CD3 x Anti-CD79B Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Human CD79B Human Inquiry
BSIG-H286 Human Anti-CD32B x Anti-CD79B Bispecific Antibody (IgG-IgG) Human IgG-IgG CD32B Human CD79B Human Inquiry
BSIG-H244 Human Anti-CD3 x Anti-CD79B Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Human CD79B Human Inquiry
CROSSAB-H286 Recombinant Human Anti-CD32B x Anti-CD79B Bispecific Antibody (CrossMab) Human CrossMab CD32B Human CD79B Human Inquiry
CROSSAB-H244 Recombinant Human Anti-CD3 x Anti-CD79B Bispecific Antibody (CrossMab) Human CrossMab CD3 Human CD79B Human Inquiry
IGFV-H286 Recombinant Human Anti-CD32B x Anti-CD79B Bispecific Antibody (IgG-scFv) Human IgG-scFv CD32B Human CD79B Human Inquiry
IGFV-H244 Recombinant Human Anti-CD3 x Anti-CD79B Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Human CD79B Human Inquiry
BSDB-H286 Recombinant Human Anti-CD32B x Anti-CD79B Bispecific Antibody (Diabody) Human Diabody CD32B Human CD79B Human Inquiry
BSDB-H244 Recombinant Human Anti-CD3 x Anti-CD79B Bispecific Antibody (Diabody) Human Diabody CD3 Human CD79B Human Inquiry
BSFAB-H286 Recombinant Human Anti-CD32B x Anti-CD79B Bispecific Antibody (Tandem Fab) Human Tandem Fab CD32B Human CD79B Human Inquiry
BSFAB-H244 Recombinant Human Anti-CD3 x Anti-CD79B Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Human CD79B Human Inquiry
BSFV-H286 Recombinant Human Anti-CD32B x Anti-CD79B Bispecific Antibody (Tandem scFv) Human Tandem scFv CD32B Human CD79B Human Inquiry
BSFV-H244 Recombinant Human Anti-CD3 x Anti-CD79B Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Human CD79B Human Inquiry
SCTB-042 Recombinant Anti-CD79B x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Mouse CD79B Mouse Inquiry
SCDB-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD32B Mouse CD79B Mouse Inquiry
SCDB-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Mouse CD79B Mouse Inquiry
FABIG-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Fab-IgG) Human Fab-IgG CD32B Mouse CD79B Mouse Inquiry
FABIG-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Mouse CD79B Mouse Inquiry
TRIB-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD32B Mouse CD79B Mouse Inquiry
TRIB-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Mouse CD79B Mouse Inquiry
BSIG-112 Anti-CD32B x Anti-CD79B Bispecific Antibody (IgG-IgG) Human IgG-IgG CD32B Mouse CD79B Mouse Inquiry
BSIG-070 Anti-CD3 x Anti-CD79B Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Mouse CD79B Mouse Inquiry
CROSSAB-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (CrossMab) Human CrossMab CD32B Mouse CD79B Mouse Inquiry
CROSSAB-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (CrossMab) Human CrossMab CD3 Mouse CD79B Mouse Inquiry
IGFV-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (IgG-scFv) Human IgG-scFv CD32B Mouse CD79B Mouse Inquiry
IGFV-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Mouse CD79B Mouse Inquiry
BSDB-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Diabody) Human Diabody CD32B Mouse CD79B Mouse Inquiry
BSDB-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Diabody) Human Diabody CD3 Mouse CD79B Mouse Inquiry
BSFAB-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Tandem Fab) Human Tandem Fab CD32B Mouse CD79B Mouse Inquiry
BSFAB-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD79B Mouse Inquiry
BSFV-112 Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Tandem scFv) Human Tandem scFv CD32B Mouse CD79B Mouse Inquiry
BSFV-070 Recombinant Anti-CD3 x Anti-CD79B Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD79B Mouse Inquiry

Background

CD79B and CD79A form heterodimers that are not covalently associated with immunoglobulin and are members of the B cell receptor complex. CD79B recognizes the B cell antigen component of the B lymphocyte antigen receptor Ig-beta protein. It is essential for the assembly, expression, and signal transduction of B cell antigen receptors. CD79B-associated proteins facilitate BCR signaling by triggering downstream activation of Bruton’s tyrosine kinase (BTK). This activates the BCM complex, ultimately leading to the NF κB pathway. CD79B is an attractive therapeutic target as it is limited to the expression of mature B cells and is almost universally present on the surface of most malignant tumors derived from B cells. Antibody-drug conjugates targeting CD79B have shown preclinical antitumor activity.

Fig.1 My-T-BCR signaling. (Young, 2019)Fig.1 My-T-BCR signaling.1

Reference

  1. Young, Ryan M., et al. "Pathogenic B‐cell receptor signaling in lymphoid malignancies: new insights to improve treatment." Immunological reviews 291.1 (2019): 190-213.
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