Creative Biolabs is a recognized leader in offering high-quality antigen and antibody conjugation services for in vitro diagnostics applications. With abundant experience and advanced technology, now we can provide oligonucleotide conjugation services with the specific antibody/oligonucleotide conjugates you require.

Introduction of Oligonucleotide Conjugation Services

Conjugation is the process of covalently linking two molecules/polymers or biomolecules/biopolymers together. Studies have shown that antibody molecules possess a number of functional groups suitable for modification or conjugation purposes. Crosslinking oligonucleotide-antibody can be achieved through lysine and N-terminal groups. During the past years, the appearance of oligonucleotide-antibody has provided an efficient and precise method for the detection of low-abundance protein. Moreover, oligonucleotide-antibody have extensively used in numerous applications from diagnostics to therapeutics, such as biomarker discovery, clinical diagnostics, and protein interaction. In addition to conjugation with an antibody, oligonucleotide-half antibody conjugation has also been developed for therapeutic and diagnostics applications.

Conjugation of azide-modified oligonucleotide to antibody.Fig.1 Conjugation of azide-modified oligonucleotide to antibody. (Gong H., 2016)

Oligonucleotide Conjugation Services Provided by Creative Biolabs

Creative Biolabs has worked in the field of IVD antibody development for many years, now we can offer high-quality oligonucleotide conjugation services as a sensitive method for protein detection and quantification. Based on our state-of-the-art platform and abundant experience, we can provide both oligonucleotide-antibody conjugation and oligonucleotide-half antibody conjugation service to promote the development of your programs. Moreover, our skilled scientists have the ability to generate conjugation in a broad range scale from 1 mg to 1 g at required antibody: oligo ratio. Furthermore, oligonucleotide conjugation services provided by Creative Biolabs have substantial high purity.

Features of Our Services

  • Professional: Performed by experienced scientists
  • Flexible service option: Agreed conjugation ration and scale
  • Short duration: Fast turnaround time with professional service
  • Reproducible: Applicable to other proteins
  • High-quality services: Well-characterized conjugation services with full of technical support

Supported by a team of scientists and experts in the field of IVD antibody development, Creative Biolabs is capable of offering a fully integrated antigen and antibody conjugation services for worldwide customers. With rich experience and advanced technology, our oligonucleotide conjugation services will be provided in the most high-quality and cost-effective way. Our professional scientists are happy to help you to make your project a success.

Additionally, we also provide other antibody conjugation service to meet every client’s specific requirements. If you are interested in the services we can provide and want to know more detailed information, please feel free to contact us and get exclusive technical support services. Our project manager will get in touch with you as soon as possible and help you design an appropriate protocol to meet your specific requirements.


  1. Gong H., (2016) "Simple method to prepare oligonucleotide-conjugated antibodies and its application in multiplex protein detection in single cells." Bioconjugate chemistry 27.1: 217-225.

For lab research use only.

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