Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsProtein Tweety homolog family in human is suggested to be integral membrane proteins which share a high degree of sequence identity. It consists of three homologs, which are known as protein tweety homolog 1 (hTTY1), protein tweety homolog 2 (hTTY2) and protein tweety homolog (hTTY3). Proteins belonging to the tweety homolog family share common structural features that contain five or six transmembrane domains positioned in a similar arrangement. This arrangement consists of a pair of transmembrane regions, followed by an additional pair of transmembrane regions and a hydrophobic region, which are followed by more transmembrane and hydrophobic regions. They have been suggested to function as chloride channels. Tweety homolog family members are large-conductance Ca²⁺-activated chloride channels and may be involved in the Ca²⁺ signal transduction.
The human protein tweety homolog family is putative maxi-chloride ion channels with differentially induced Cl-channel activity. hTTY1 is a volume-regulated Cl-channel, whose activity is related to cell swelling, while the activity of hTTY2 and hTTY3 is related to ionomycin and calcium ions. Here, the three members of protein tweety homolog family are covered in further detail.
Using our Magic™ membrane protein production platform, experts in Creative Biolabs are very experienced in providing the protein preparation services of these membrane proteins mentioned above in required formats through different strategies, including detergent micelles, proteoliposomes, nanodiscs, lipoparticles, polymers, with stable cell lines.
Additionally, Magic™ membrane protein antibody discovery platform in Creative Biolabs can be applied in developing antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology, and etc. We also present DNA immunization service for anti-membrane protein antibody development. Please feel free to contact us for technical help.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
