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Yeast Display Library Construction Services

At Creative Biolabs, we specialize in the construction of yeast display libraries to facilitate the discovery of high-affinity binders for your research and therapeutic needs. Our expert team offers the most extensive portfolio of yeast display library construction services tailored to your specific needs.

Services Workflow Advantages Applications Case

Yeast Display Library Construction in Creative Biolabs

Yeast display's eukaryotic expression system offers unparalleled capabilities for displaying and engineering proteins that are challenging to produce with other systems. As a global leader in antibody discovery, Creative Biolabs brings extensive expertise in yeast display library construction, leveraging our proprietary Ultraff™ Yeast Display Platform.

Our comprehensive yeast display library construction services include:

Fig.·1·Yeast display antibody library construction (Creative Biolabs·AI)
Yeast Display Antibody Library Construction
Fig.·2·Yeast display non-antibody protein library construction (Creative Biolabs·AI)
Yeast Display Non-Antibody Protein Library Construction
Fig. 3 Yeast display peptide library construction (Creative Biolabs·AI)
Yeast Display Peptide Library Construction
Fig. 4 Yeast display cDNA library construction (Creative Biolabs·AI)
Yeast Display cDNA Library Construction

Workflow

The process of constructing yeast display libraries at Creative Biolabs involves several key steps, each meticulously designed to ensure the creation of high-quality, diverse libraries for various applications. Here is an overview of our workflow:

Advantages of Yeast Display Library Construction Service


Superior Eukaryotic Expression
Accurate protein folding and modification to ensure proper protein conformation and post-translational modifications. Unbiased compared to phage display.
Ideal for challenging targets (e.g., membrane proteins and conformationally sensitive antigens.)

Comprehensive Libraries
Antibody, non-antibody protein, peptide, and cDNA.

Enhanced Library Diversity
Advanced library construction methods and protocols.

Rigorous Library Quality Control (QC)
Validation of diversity, integrity, and functionality display through various methods.

Robust Screening and Validation Systems
High-affinity binder isolation to achieve picomolar (pM) affinity.

Flexible Solutions
Utilizing the exclusive Ultraff™ yeast display platform.

Applications of Yeast Display Libraries

Yeast display libraries provide a versatile and powerful platform for a wide range of applications in biotechnology and biomedical research. The ability to express proteins on the surface of yeast cells in a eukaryotic environment provides several advantages, making yeast display an invaluable tool for numerous applications:

  • Therapeutic Antibody Discovery (IgG, Fab, scFv, sdAb, etc)
  • Antibody Engineering (Humanization, Affinity Maturation)
  • Protein Engineering (Optimization of Protein Properties)
  • Enzyme Immobilization
  • Vaccine Development
  • Protein-Protein Interaction Studies
  • T Cell Receptor Engineering

Case for Yeast Display scFv Library Construction

PCR Assembling ScFv

Fig. 5 PCR assembling scFv (Creative Biolabs Original)

Good Display Efficiency Tested by FACS

Fig. 6 Good display efficiency tested by FACS (Creative Biolabs Original)

Utilizing cutting-edge technology and a rigorous workflow, our scientists are dedicated to constructing high-quality yeast display libraries for clients worldwide. Contact us today to discuss your antibody library construction needs and discover how we can help you achieve your research goals.


All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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