RYK mAb (484834) B Cell Engineering Specific Plasmid (CAT#: BGS-1223-CR15)

This product is a B cell engineering plasmid designed by genomic integration of B cell receptors (RFP-SV40-Tat/SPI-CD79α-CD8-His) and CRISPR-Cas (Cas13c (C2c7)-RNA-HD/Cas3-Stat5a) systems. This product can precisely introduce cassettes of several kb size into the genome of various B cells to enhance surface expression and antigen recognition of a synthetic BCRs.

Datasheet

Specifications

Clone 484834
Host Mouse
Targeting Cell Type DG-75 [D.G.-75]
Reporter gene RFP
Promoter SV40
Signal peptides Tat/SPI
Signaling domains CD79α
TM domains CD8
Detection tags His
Linkers Short Flexible Linker
Co-Receptors CD19
Vector Type AAV
Vector Name BGpCDH1
Class 1 multi-Cas
Type VI
Subtype A, B, C, D
Effector Cas13c (C2c7)
DNA Type RNA
Nuclease domains HD/Cas3
TracrRNA requirement No
PAM/PFS -
Insertion Stat5a
Construction RFP-SV40-CD79α-Cas13c (C2c7)-RNA-Stat5a

Target Information

Target RYK
Alternative Names RYK; D3S3195; JTK5; JTK5A; RYK1; receptor-like tyrosine kinase; receptor like tyrosine kinase

Product Properties

Format Liquid/lyophilized
Shipping It is usually shipped overnight at room temperature in small cardboard boxes. If hot temperatures are expected during transit, they will be shipped in polystyrene containers with gel ice packs.
Handling Advice No special measures are necessary. Keep away from food, drink and animal feedingstuffs.
Storage Plasmid (lyophilized), short-time storage at Room Temperature, recommended store at -20°C or -80°C ; Plasmid (Liquid), blue ice store at 4°C.
COA

Certificate of Analysis Lookup

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